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Plant Stanol Ester: Cholesterol (in statin treated diabetics)

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By: Sean Moloughney

Editor, Nutraceuticals World

Nutraceutical: Benecol (plant stanol ester)
 
Indication: Cholesterol (in statin-treated diabetics)
 
Source: Atherosclerosis, 2011;doi:10.1016/ j.atherosclerosis.2011.03.041.
 
Research: This study, carried out at the University of Eastern Finland in Finland, recruited 24 participants with type 1 diabetes who were on stable cholesterol-lowering statin medication. The mean baseline LDL-cholesterol concentration was 2 mmol/l. The subjects consumed either plant stanol ester-containing vegetable oil-based spread (intervention group) or a corresponding control spread without plant stanol ester (control group) for 4 weeks. The intake of plant stanols in the intervention group was 3 grams per day. The subjects were advised to make no changes to their usual diet and lifestyle and to remain on their prescribed statin treatment.
 
Results: The results showed that plant stanol ester effectively lowered cholesterol. Total and “bad” LDL-cholesterol were reduced by 8% and 15%, respectively, in the intervention group compared with the control group, while triglyceride concentrations and “good” HDL-cholesterol remained unchanged.

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